Overview

Adrenocortical cancer is a rare disease in which cancer forms in the cortex (outer layer) of an adrenal gland. There are two adrenal glands. One sits on top of each kidney. The adrenal cortex makes important hormones, including ones that keep water and salt in balance, control blood pressure, and help the body use energy.

Adrenocortical tumors usually make extra amounts of one or more adrenal hormones, which may cause symptoms.

Certain inherited disorders increase the risk of adrenocortical cancer. These include Li-Fraumeni syndrome, Beckwith-Wiedemann syndrome, and Carney complex.

Adrenocortical cancer may also be called adrenal cortical carcinoma.

Anatomy of the adrenal gland. There are two adrenal glands, one on top of each kidney. The outer part of each gland is the adrenal cortex; the inner part is the adrenal medulla.

Anatomy of the adrenal gland. There are two adrenal glands, one on top of each kidney.

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Adrenocortical Carcinoma

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